#RsearchSpeak & #Neurospeak: the great differentiator   Anti-drug antibodies are a major problem in clinical practice and are important for safety and efficacy reasons. #ResearchSpeak #ClinicSpeak #MSBlog  How important are anti-drug antibodies in relation to biological therapies in particular neutralising antibodies to the monoclonal therapies used to treat MS?  This issue became a defining issue in rheumatology amongst the monoclonal anitbodies targeting TNF-alpha. Infliximab the initial…

#RsearchSpeak & #Neurospeak: the great differentiator Anti-drug antibodies are a major problem in clinical practice and are important for safety and efficacy reasons. #ResearchSpeak #ClinicSpeak #MSBlog How important are anti-drug antibodies in relation to biological therapies in particular neutralising antibodies to the monoclonal therapies used to treat MS? This issue became a defining issue in rheumatology amongst the monoclonal anitbodies targeting TNF-alpha. Infliximab the initial…

Tysabri Protects Against Relapse in Multiple Sclerosis, patients are a a high risk for developing PML. Many multiple sclerosis patients are also treated with natalizumab, which is an monoclonal antibody immunosuppressive medication. Putting the two together, some multiple sclerosis patients see a risk for extended use of Tysabri and desire a different treatment. “It’s difficult for patients to make decisions,   In his experience, when the risk of PML for multiple scleros

Tysabri Protects Against Relapse in Multiple Sclerosis, According To Study

Tysabri Protects Against Relapse in Multiple Sclerosis, patients are a a high risk for developing PML. Many multiple sclerosis patients are also treated with natalizumab, which is an monoclonal antibody immunosuppressive medication. Putting the two together, some multiple sclerosis patients see a risk for extended use of Tysabri and desire a different treatment. “It’s difficult for patients to make decisions, In his experience, when the risk of PML for multiple scleros

Sclérose en plaques : éviter le natalizumab (Tysabri) et l'alemtuzumab (Lemtrada), conseille Prescrire | Psychomédia

Sclérose en plaques : éviter le natalizumab (Tysabri) et l'alemtuzumab (Lemtrada), conseille Prescrire | Psychomédia

Natalizumab (Tysabri) and PML risk: an update     Progressive Multifocal Leukoencephalopathy is a life-threatening progressive demyelinating disease affecting the white matter tracts of the brain. It is caused by reactivation of the John Cunningham (JC) virus. Although JC virus infects 80  90% of the worlds population PML is exceptionally rare and almost exclusively occurs in people who are immunosuppressed either due to a disease such as HIV/AIDS or due to medication.   In the MS world…

Natalizumab (Tysabri) and PML risk: an update Progressive Multifocal Leukoencephalopathy is a life-threatening progressive demyelinating disease affecting the white matter tracts of the brain. It is caused by reactivation of the John Cunningham (JC) virus. Although JC virus infects 80 90% of the worlds population PML is exceptionally rare and almost exclusively occurs in people who are immunosuppressed either due to a disease such as HIV/AIDS or due to medication. In the MS world…

#NeuroSpeak: treating MS in patients with PML   Teriflunomide is the drug of choice for treating MS in patients recovering from PML. #NeuroSpeak #CharcotProject Summary: This post summarises the scientific principles for treating multiple sclerosis in patients who have PML as a complication of natalizumab treatment. I make the case for using DMTs that are not immunosuppressive and highlight the antiviral effects of Teriflunomide that make it the DMT of choice. At the grand round at Imperial…

#NeuroSpeak: treating MS in patients with PML Teriflunomide is the drug of choice for treating MS in patients recovering from PML. #NeuroSpeak #CharcotProject Summary: This post summarises the scientific principles for treating multiple sclerosis in patients who have PML as a complication of natalizumab treatment. I make the case for using DMTs that are not immunosuppressive and highlight the antiviral effects of Teriflunomide that make it the DMT of choice. At the grand round at Imperial…

Sclérose en plaques : éviter les médicaments natalizumab (Tysabri) et alemtuzumab (Lemtrada), selon Prescrire | PsychoMédia

Sclérose en plaques : éviter les médicaments natalizumab (Tysabri) et alemtuzumab (Lemtrada), selon Prescrire | PsychoMédia

MS News Clinical Trial Leaderboard Registry Ad

New Multiple Sclerosis Drug May Repair Nerve Demyelination

MS News Clinical Trial Leaderboard Registry Ad

Woman with PML Linked to MS Therapy Successfully Treated with IL-2 Cytokine May 19, 2016	Magdalena Kegelby Magdalena Kegel  In News.

Woman with PML Linked to MS Therapy Successfully Treated with IL-2 Cytokine

Woman with PML Linked to MS Therapy Successfully Treated with IL-2 Cytokine May 19, 2016 Magdalena Kegelby Magdalena Kegel In News.

http://www.mscenter.org/about-us/news-room/news/433-new-study-shows-natalizumab-tysabri-significantly-improves-cognitive-impairment-over-three-years-in-ms-patients

http://www.mscenter.org/about-us/news-room/news/433-new-study-shows-natalizumab-tysabri-significantly-improves-cognitive-impairment-over-three-years-in-ms-patients

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