The Tibetan Mastiff is one of the most costly dogs. price runs to about $582,000. it is one of the largest dog breeds worldwide standing more than 32 inches tall, with a weight of over 150 lbs. These dogs come in colors, including black, brown, red and gray. Pure white Tibetan Mastiffs are extremely rare. Are known for not having the same unpleasant odor of many dogs. Respected guardians of farm, extremely protective, some having killed tigers before to safeguard their flock.